Y2 Pharm Theory Notes: Biologics
❌🧇 Notes: Y2 pharm theory – biologics Similar resources: y2pharmtheory biologics Biologics- peptides/ proteins, sugars or nucleic acids. Produced by an organismwhich has been genetically engineered to synthesise the biologic.• Biosimilar- almost identical copy of the innovator biologic• SME (small molecular entity)- chemical with low molecular weight (normaldrug)• Generic drug- copy of innovator drug when […]
Y2 Pharm Notes: Antivirals
❌🧇 Notes: Y2 GDC Pharm – antivirals Similar resources: • Viral Life Cycle:1. attachment and entry2. viral nucleic acid replication3. production and processing of viral proteins and coat assembly of virions4. viral release and shedding• Targets:1. attachment2. reverse transcriptase3. viral protease4. viral DNA polymerase5. protein translation and assembly of virus6. inhibit viral shedding• Nucleoside Reverse […]
Y2 Pharm Notes: Antibiotics
❌🧇 Notes: Y2 GDC Pharm – antibiotics Similar resources: GDC pharm immunedrugs Pharmacology: Pharmacology ofAntibacterial Drugs• bactericidal antibiotics- kill bacteria• bacteriostatic antibiotics- slow bacteria proliferation by lowering divisions• Targets for bacteria:o Cell wall synthesis or destruction▪ gram positive: peptidoglycan (stains purple)▪ gram negative: lipopolysaccharide (stain pink)▪ mycobacteria: mycolic acid▪ fungi: ergosterol cell wall composition▪ beta-lactams […]