Paraneoplastic Syndrome:
Cachexia:
Β
Hormone Based therapyβ’ Protein Kinases inhibitorsβ’ Monoclonal antibodiesβ’ antineoplastic drugsβ’ cell based therapies
Goldie-Coldman hypothesis:o the probability of a resistance cell occurring = number of cells xmutation rate
β’ Combining drugs works better if:o there is a significant therapeutic benefit compared to monotherapyo doesnβt result in unacceptable toxicity