πŸ–‹οΈ Notes: Y2 pharm - cancer chemotherapy

Similar resources:

Paraneoplastic Syndrome:

Cachexia:

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Hormone Based therapy
β€’ Protein Kinases inhibitors
β€’ Monoclonal antibodies
β€’ antineoplastic drugs
β€’ cell based therapies

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Goldie-Coldman hypothesis:
o the probability of a resistance cell occurring = number of cells x
mutation rate

β€’ Combining drugs works better if:
o there is a significant therapeutic benefit compared to monotherapy
o doesn’t result in unacceptable toxicity