Notes: Y2 pharm - Congestive heart failure
Similar resources:
Y2heartpharm, CHF, vasodilators
anti-thrombotic- warfarin (anticoagulant), aspirin (antiplatelet)
o statin- only help patients with hypercholesterolaemia or ischaemic heart
disease
o non-dihydropyridine calcium channel blocker- (verapamil) harmful due
to negative inotropic action
o NSAIDs- (ibuprofen)- promotes water and salt retention (harmful)
Beta-Blockers: bisoprolol, carvedilol, ramipiril, captopril, losartan , nitrates, spironolactone , sacubitril
ACE inhibitors:
Angiotensin Receptor blockers:
Vasodilators:
Mineralocorticoid receptor antagonists:
Sacubitril Valsartan:
DIURETICS
Digoxin:
Angiotensin-Converting Enzyme (ACE) Inhibitors
Commonly prescribed include:
- Captopril (Capoten)
- Enalapril (Vasotec)
- Fosinopril (Monopril)
- Lisinopril (Prinivil, Zestril)
- Perindopril (Aceon)
- Quinapril (Accupril)
- Ramipril (Altace)
- Trandolapril (Mavik)
Angiotensin II Receptor Blockers (or Inhibitors)
(Also known as ARBs or Angiotensin-2 Receptor Antagonists)
Commonly prescribed include:
- Candesartan (Atacand)
- Losartan (Cozaar)
- Valsartan (Diovan)
Angiotensin-Receptor Neprilysin Inhibitors (ARNIs)
ARNIs are a new drug combination of a neprilysin inhibitor and an ARB.
- Sacubitril/valsartan
IfΒ Channel Blocker (or inhibitor)
This drug class reduces the heart rate, similar to another class of drugs called beta blockers.
- Ivabradine (Corlanor)
Beta Blockers (Also known as Beta-Adrenergic Blocking Agents)
Commonly prescribed include:
- Bisoprolol (Zebeta)
- Metoprolol succinate (Toprol XL)
- Carvedilol (Coreg)
- Carvedilol CR (Coreg CR) Toprol XL
Aldosterone Antagonists
Commonly prescribed include:
- Spironolactone (Aldactone)
- Eplerenone (Inspra)
Hydralazine and isosorbide dinitrate (specifically benefits African-Americans with heart failure)
Commonly prescribed:
- Hydralazine and isosorbide dinitrate (combination drug) – (Bidil)
Diuretics (Also known as water pills)
Commonly prescribed include:
- Furosemide (Lasix)
- Bumetanide (Bumex)
- Torsemide (Demadex)
- Chlorothiazide (Diuril)
- Amiloride (Midamor Chlorthalidone (Hygroton)
- Hydrochlorothiazide or HCTZ (Esidrix, Hydrodiuril)
- Indapamide (Lozol)
- Metolazone (Zaroxolyn)
- Triamterene (Dyrenium)